Test Details

• Discipline:

  Biochemistry

  Biochemistry

• Specimen Container Adult:

  Serum

  Serum

• Specimen Container Paediatric:

  Serum

  Serum

• Minimum Volume Adult:

  2 mL

  2 mL

• Minimum Volume Paediatric:

  2 mL

  2 mL

• Special Requirement:

  Store sample at 4°C

  Store sample at 4°C

• Transport Requirements:

  Post at room temperature

  Post at room temperature

• Interpretation:

  A1AG is a 40kDa glycoprotein. It is a 'slow' acute phase reactant. Serum levels are increased in inflammation, tissue necrosis and malignancy. Reduced serum levels are seen during pregnancy and as ...

  A1AG is a 40kDa glycoprotein. It is a 'slow' acute phase reactant. Serum levels are increased in inflammation, tissue necrosis and malignancy. Reduced serum levels are seen during pregnancy and as a result of treatment with exogenous oestrogens. It is of little use in the assessment of the acute phase response though it may be useful as a marker of activity in IBD.

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• Reference Ranges:

  Paediatric

  <1y: 0.4 - 1.0 g/L

  Male

  1 - 50y: 0.6 - 1.2 g/L

  50+ y: 0.8 - 2.0 g/L

  Female

  1 - 50y: 0.4 - 1.0 g/L

  50+ y: 0.8 - 2.0 g/L

  Paediatric

  <1y: 0.4 - 1.0 g/L

  Male

  1 - 50y: 0.6 - 1.2 g/L

  50+ y: 0.8 - 2.0 g/L

  Female

  1 - 50y: 0.4 - 1.0 g/L

  50+ y: 0.8 - 2.0 g/L

• Factors Affecting Result:

  Very lipaemic or tubid samples, Haemolysis. EDTA, citrate, and oxalate anticoagulants.

  Very lipaemic or tubid samples, Haemolysis. EDTA, citrate, and oxalate anticoagulants.

• Routine Contact Name:

  Duty Biochemist

• Routine Telephone:

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

• Routine Email:

  nuth.dutybiochemist@nhs.net