Albumin, urine
Clinical Background:
Microalbuminuria has been shown to predict the later development of established clinical diabetic nephropathy in insulin dependent diabetics and of diabetic nephropathy and increased mortality in...
Microalbuminuria has been shown to predict the later development of established clinical diabetic nephropathy in insulin dependent diabetics and of diabetic nephropathy and increased mortality in non-insulin dependent patients.
The rate of progressive deterioration of renal function may be slowed, stabilised or even reversed with improved glucose control by means of multiple injections or infusion pumps, hypertension treatment and dietary protein restriction. Early intervention (i.e. before development of clinical proteinuria) appears to be much more effective.
Test Details
-
Discipline:
Biochemistry
Biochemistry
-
Specimen Container Adult:
Plain universal tube (random collection) or 24-hour urine container
Plain universal tube (random collection) or 24-hour urine container
-
Specimen Container Paediatric:
Plain universal tube
Plain universal tube
-
Minimum Volume Adult:
6 µL (+100 µL dead volume)
6 µL (+100 µL dead volume)
-
Minimum Volume Paediatric:
6 µL (+100 µL dead volume)
6 µL (+100 µL dead volume)
-
Special Requirement:
Ideal sample required is the second void urine sample.
Ideal sample required is the second void urine sample.
-
Sample Stability:
7 days at 15-25C
1 month at 2-8C
7 days at 15-25C
1 month at 2-8C
-
Quality Assurance:
WEQAS
WEQAS
-
Reference Ranges:
Microalbumin:Creatinine Ratio:
0 - 3 mg/mmol creatinine
Microalbumin:Creatinine Ratio:
0 - 3 mg/mmol creatinine
-
Factors Affecting Result:
Erect posture and acute diuresis increase urinary albumin production.
False positive results can be caused by contamination with menstrual or seminal fluid, or by a urinary tract infection.
High ur...
Read MoreErect posture and acute diuresis increase urinary albumin production.
False positive results can be caused by contamination with menstrual or seminal fluid, or by a urinary tract infection.
High urine volumes in poorly controlled diabetic patients may cause false negative albumin results.
-
Routine Contact Name:
Duty Biochemist
-
Routine Telephone:
Freeman: 0191 244 8889
RVI: 0191 282 9719Freeman: 0191 244 8889
RVI: 0191 282 9719 -
Routine Email: