Newcastle Laboratories

Activated Partial Thromboplastin Ratio

Clinical Background:

The APTR is used to control Unfractionated Heparin therapy. The patients Activated Partial Thromboplastin Time (APTT) is divided by the laboratory Mean Normal Activated Partial Thromboplastin Time ...

The APTR is used to control Unfractionated Heparin therapy. The patients Activated Partial Thromboplastin Time (APTT) is divided by the laboratory Mean Normal Activated Partial Thromboplastin Time (MNAPTT). There is some variation in APTT reagent sensitivity to Heparin and local ranges may vary depending on reagent used, however the general accepted therapeutic range is a ratio of 1.5 - 2.5

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Specimen Container Paediatric:

    Light blue - sodium citrate

    Light blue - sodium citrate

  • Minimum Volume Adult:

    2.7mL

    2.7mL

  • Minimum Volume Paediatric:

    1.3mL

    1.3mL

  • Special Requirement:

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    8 hrs

    8 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    Continuous

    Continuous

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs....

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Blood Coagulation

    UK NEQAS Blood Coagulation

  • Reference Ranges:

    1.5 - 2.5

    1.5 - 2.5

  • Other Info:

    For monitoring therapeutic dosing of heparin.

    For monitoring therapeutic dosing of heparin.

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 282 0332

    0191 282 0332

  • Routine Email:

  • Specialist Test:

    No

    No

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All times, both sites

Turn Around:

Urgent within 1 hour.

Routine within 4 hours.

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