Newcastle Laboratories

Acetylcholine Receptor Antibodies

Clinical Background:

Acetylcholine Receptor Antibodies (ACRA) are found in 85% of patients with Myasthenia Gravis. Antibodies may persist even when the disease is in remission. ACRA are also seen in patients with thymo...

Acetylcholine Receptor Antibodies (ACRA) are found in 85% of patients with Myasthenia Gravis. Antibodies may persist even when the disease is in remission. ACRA are also seen in patients with thymoma and penicillamine-induced myasthenia.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Add On Test:

    All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address

    nuth.autoimmunity@nhs.net

    All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address

    nuth.autoimmunity@nhs.net

  • Interpretation:

    About 10% of patients with myasthenia may have no detectable AchRAbs. Patients with ocular myasthenia may have negative AchRAbs.

    About 10% of patients with myasthenia may have no detectable AchRAbs. Patients with ocular myasthenia may have negative AchRAbs.

  • Reference Ranges:

    Normal Range: 0.0 - 0.2 nmol/L

    Normal Range: 0.0 - 0.2 nmol/L

  • Other Info:

    Reported as a value to 1 decimal place.

    Reported as a value to 1 decimal place.

  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

  • Specialist Email:

    nuth.autoimmunity@nhs.net

    nuth.autoimmunity@nhs.net

Availability:

Sent to an external laboratory for testing.

Turn Around:

Approx. 3 weeks

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