Newcastle Laboratories

17-alpha-Hydroxyprogesterone, bloodspot

Clinical Background:

The measurement of 17a-hydroxy-progesterone in dried blood spots is used in the monitoring and 'fine tuning' of corticosteroid therapy used in the treatment of Congenital Adrenal Hyperplasia

The measurement of 17a-hydroxy-progesterone in dried blood spots is used in the monitoring and 'fine tuning' of corticosteroid therapy used in the treatment of Congenital Adrenal Hyperplasia

Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Bloodspot guthrie card, Lithium Heparin sample

    Bloodspot guthrie card, Lithium Heparin sample

  • Specimen Container Paediatric:

    Bloodspot guthrie card, Lithium Heparin sample

    Bloodspot guthrie card, Lithium Heparin sample

  • Minimum Volume Adult:

    3.2mm bloodspot

    3.2mm bloodspot

  • Minimum Volume Paediatric:

    3.2mm bloodspot

    3.2mm bloodspot

  • Sample Stability:

    1 month

    1 month

  • Transport Requirements:

    Ambient

    Ambient

  • Freq Analysis:

    As required or weekly 

    As required or weekly 

  • Add On Test:

    Not possible

    Not possible

  • Quality Assurance:

    CDC

    CDC

  • Interpretation:

    Ideally the blood spot 17aOHP should fluctuate minimally throughout a 24 hour period.

    Ideally the blood spot 17aOHP should fluctuate minimally throughout a 24 hour period.

  • Reference Ranges:

    No reference ranges available for Bloodspot 17aOHP.

    Please consult Duty Biochemist when guidance is required.

    No reference ranges available for Bloodspot 17aOHP.

    Please consult Duty Biochemist when guidance is required.

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    RVI: 0191 282 9719

    Freeman: 0191 244 8889

    RVI: 0191 282 9719

    Freeman: 0191 244 8889

  • Routine Email:

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    New Born Screening;

    New Born Screening;

  • Specialist Telephone:

    0191 282 0339

    0191 282 0339

  • Specialist Email:

    Tnu-tr.newcastlenewbornscreening@nhs.net

    Tnu-tr.newcastlenewbornscreening@nhs.net

Availability:

All testing is performed at RVI Newborn Screening laboratory and available during routine hours, Monday to Friday. Testing is usually performed on a weekly basis, depending on batch size availability.

Turn Around:

Usually within 7 days

Send To:

Department of Blood Sciences - Newborn Screening

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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