Newcastle Laboratories

Procalcitonin

Clinical Background:

Increased procalcitonin concentrations are often found in patients suffering from bacterial sepsis, especially severe sepsis and septic shock. Procalcitonin is considered as a prognostic marker to ...

Increased procalcitonin concentrations are often found in patients suffering from bacterial sepsis, especially severe sepsis and septic shock. Procalcitonin is considered as a prognostic marker to support outcome prediction in sepsis patients.

In patients suffering from community-acquired respiratory tract infections or ventilator‑induced pneumonia procalcitonin has been proposed as a guide for the decision of antibiotic treatment necessity and to monitor treatment success.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Specimen Container Paediatric:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Minimum Volume Adult:

    1 mL blood

    1 mL blood

  • Minimum Volume Paediatric:

    0.5 mL blood

    0.5 mL blood

  • Sample Stability:

    Unseparated sample: 24 hours

    Separated sample:

    - at 15-25C: 24 hours

    - at 4ºC: 2 days

    - at -20C: 13 months

    Unseparated sample: 24 hours

    Separated sample:

    - at 15-25C: 24 hours

    - at 4ºC: 2 days

    - at -20C: 13 months

  • Reference Ranges:

    < 0.5 ng/mL represent a low risk of severe sepsis and/or septic shock

    >2.0 ng/mL represent a high risk of severe sepsis and/or septic shock

    < 0.5 ng/mL represent a low risk of severe sepsis and/or septic shock

    >2.0 ng/mL represent a high risk of severe sepsis and/or septic shock

  • Other Info:

    Lithium heparin plasma sample also acceptable

    Lithium heparin plasma sample also acceptable

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

Available 24/7

Site of analysis: RVI

Turn Around:

Urgent: within 1 hour

Non-urgent: within 4 hours

Send To:

Department of Blood Sciences 
Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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