Test Details

• Discipline:

  Biochemistry

  Biochemistry

• Specimen Container Adult:

  Random urine sample (plain universal container) or 24 hour urine collection (plain or acid rinsed bottle)

  Random urine sample (plain universal container) or 24 hour urine collection (plain or acid rinsed bottle)

• Specimen Container Paediatric:

  Random urine sample (plain universal container)

  Random urine sample (plain universal container)

• Minimum Volume Adult:

  1 mL

  1 mL

• Minimum Volume Paediatric:

  1 mL

  1 mL

• Special Requirement:

  Urine samples should be fresh or acidified to reduce the formation of insoluble calcium phosphate complexes.
  A 24 h collection may be taken to reduce the effect of diurnal variation and diet on ph...

  Urine samples should be fresh or acidified to reduce the formation of insoluble calcium phosphate complexes.
  A 24 h collection may be taken to reduce the effect of diurnal variation and diet on phosphate excretion.
  If the sample is to be used for calculation of renal tubular reabsorption of phosphate (TmP/GFR), it should be taken into a plain bottle, fasting, together with a serum sample, to allow simultaneous measurement of serum phosphate,
  and urine and serum creatinine.

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• Sample Stability:

  Unknown at 15-25C, 6 months at 2-8C, unknown at -20C

   

  Unknown at 15-25C, 6 months at 2-8C, unknown at -20C

   

• Interpretation:

  Urine phosphate is measured together with serum phosphate, and urine and serum creatinine, to enable calculation of the renal tubular
  reabsorption of phosphate (TmP/GFR), which can be used to inve...

  Urine phosphate is measured together with serum phosphate, and urine and serum creatinine, to enable calculation of the renal tubular
  reabsorption of phosphate (TmP/GFR), which can be used to investigate the cause of hypophosphataemia. A low TmP/GFR is found
  in several disorders of renal phosphate handling that result in hyperphosphaturia, hypophosphataemia and osteomalacia.

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• Reference Ranges:

  24hr urine:
  Adult: 15 - 50 mmol/24hr

  Random urine: (mmol/mmol creatinine)
  6 - 12 months: 1.2 - 19.0
  1 - <2 years: 1.2 - 14.0
  2 - <3 years: 1.2 - 12.0
  3 - <5 years: 1.2 - 8.0
  5 - <7 years: 1.2 - 5.0...

  24hr urine:
  Adult: 15 - 50 mmol/24hr

  Random urine: (mmol/mmol creatinine)
  6 - 12 months: 1.2 - 19.0
  1 - <2 years: 1.2 - 14.0
  2 - <3 years: 1.2 - 12.0
  3 - <5 years: 1.2 - 8.0
  5 - <7 years: 1.2 - 5.0
  7 - <10 years: 1.2 - 3.6
  10 - <14 years: 0.8 - 3.2
  14 - <17 years: 0.8 - 2.7
  
  

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• Factors Affecting Result:

  Urine phosphate excretion varies with age, time of day, renal function,
  plasma PTH concentration, muscle mass and diet. Renal tubular reabsorption of phosphate (TmP/GFR) is considered to be a bett...

  Urine phosphate excretion varies with age, time of day, renal function,
  plasma PTH concentration, muscle mass and diet. Renal tubular reabsorption of phosphate (TmP/GFR) is considered to be a better measure of renal
  phosphate handling.

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• Routine Contact Name:

  Duty Biochemist

• Routine Telephone:

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

  Freeman: 0191 244 8889
  RVI: 0191 282 9719

• Routine Email:

  nuth.dutybiochemist@nhs.net