Newcastle Laboratories

pH, fluid

Clinical Background:

Pleural fluid acidosis reflects an increase in lactic acid and carbon dioxide production due to a local increase in metabolic activity.The main use of pleural fluid pH is in aiding in the decision ...

Pleural fluid acidosis reflects an increase in lactic acid and carbon dioxide production due to a local increase in metabolic activity.The main use of pleural fluid pH is in aiding in the decision to treat pleural infection with tube drainage. Measurement of pH in any other fluid is not likely to be helpful.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Arterial blood gas syringe collected anaerobically

    Arterial blood gas syringe collected anaerobically

  • Specimen Container Paediatric:

    Arterial blood gas syringe collected anaerobically

    Arterial blood gas syringe collected anaerobically

  • Minimum Volume Adult:

    1 mL fluid

    1 mL fluid

  • Minimum Volume Paediatric:

    1 mL fluid

    1 mL fluid

  • Special Requirement:

    Send to lab ASAP.Samples which are too viscous and/or contain particulate matter after centrifugation are unsuitable for analysis.

    Send to lab ASAP.Samples which are too viscous and/or contain particulate matter after centrifugation are unsuitable for analysis.

  • Interpretation:

    Pleural fluid pH less than 7.3 may suggest malignant effusion, complicated pleural infection, connective tissue disease, tuberculous effusion and oesophageal rupture.
    pH less than 7.2 suggests a pa...

    Pleural fluid pH less than 7.3 may suggest malignant effusion, complicated pleural infection, connective tissue disease, tuberculous effusion and oesophageal rupture.
    pH less than 7.2 suggests a parapneumonic effusion or empyema and may require drainage.

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  • Reference Ranges:

    pH > 7.3 considered normal.

    pH > 7.3 considered normal.

  • Routine Contact Name:

    Duty biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

24/7, analysed at RVI and Freeman

Turn Around:

Within 1 hour

 

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