Newcastle Laboratories

Paraproteins (in serum)

Clinical Background:

Guidelines for the Interpretation and Management of immunoglobulins and Paraproteins in Adults.pdf

 

Monoclonal paraprotein bands in the serum are seen in myeloma and in some non-malignant or pre-m...

Guidelines for the Interpretation and Management of immunoglobulins and Paraproteins in Adults.pdf

 

Monoclonal paraprotein bands in the serum are seen in myeloma and in some non-malignant or pre-malignant conditions. Discussion with a haematologist is recommended. Single or multiple small paraprotein bands may be seen in chronic infectious or inflammatory conditions.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Not applicable

    Not applicable

  • Specimen Container Paediatric:

    Not applicable

    Not applicable

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Daily

    Daily

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS for MONOCLONAL PROTEIN IDENTIFICATION

    UK NEQAS for MONOCLONAL PROTEIN IDENTIFICATION

  • Interpretation:

    None

    None

  • Reference Ranges:

    Normal Range: Adults (<75 years): Absent Adults (>75 years): Present at low levels (<10g/L) in up to 20% of patients

    Normal Range: Adults (<75 years): Absent Adults (>75 years): Present at low levels (<10g/L) in up to 20% of patients

  • Other Info:

    All requests for Immunoglobulins (Igs) are examined for paraprotein bands by electrophoresis (EP) (see serum electrophoresis). If a paraprotein band is detected it is quantitated by densitometry wh...

    All requests for Immunoglobulins (Igs) are examined for paraprotein bands by electrophoresis (EP) (see serum electrophoresis). If a paraprotein band is detected it is quantitated by densitometry where possible and a result given in g/L. Further investigations will define the nature of the paraprotein (see immunofixation).

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  • Routine Contact Name:

    Proteins Lab

  • Routine Telephone:

    0191 282 4766

    0191 282 4766

  • Routine Email:

Availability:

Serum Protein Electrophoresis gels are run several times a day Monday to Friday 08:30 to 17:00.

Turn Around:

3 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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