Molecular single gene tests for haematological malignancy
Clinical Background:
We employ a number of methods such as Sanger sequencing, MassARRAY using mass spectrometry technology (MALDI-TOF – Matrix-assisted laser desorption/ionisation – time of flight) and targeted PCR fra...
We employ a number of methods such as Sanger sequencing, MassARRAY using mass spectrometry technology (MALDI-TOF – Matrix-assisted laser desorption/ionisation – time of flight) and targeted PCR fragment analysis. These genomic changes can help in the diagnosis and prognosis of haematological malignancies. Molecular tests are requested by a consultant haematologist or histopathologist depending on the morphological or immunophenotypic results.
Test Details
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Discipline:
NEHODS
NEHODS
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Specimen Container Adult:
EDTA for liquid samples and FFPE for tissue biopsies
EDTA for liquid samples and FFPE for tissue biopsies
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Specimen Container Paediatric:
EDTA for liquid samples and FFPE for tissue biopsies
EDTA for liquid samples and FFPE for tissue biopsies
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Minimum Volume Adult:
3ml
3ml
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Minimum Volume Paediatric:
3ml
3ml
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Special Requirement:
Please complete NEHODS request form
Please complete NEHODS request form
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Sample Stability:
N/A
N/A
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Transport Requirements:
Samples should be sent to laboratory immediately.
Samples should be sent to laboratory immediately.
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Freq Analysis:
Daily
Daily
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Add On Test:
Can be added to any genetics sample where DNA has been stored
Can be added to any genetics sample where DNA has been stored
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Quality Assurance:
UK NEQASLI
UK NEQASLI
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Interpretation:
By genetics clinical scientist
By genetics clinical scientist
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Reference Ranges:
N/A
N/A
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Factors Affecting Result:
Quality and size of sample
Quality and size of sample
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Referenced Documents:
N/A
N/A
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Other Info:
Includes analysis of FLT3, NPM1, KIT, BRAF, MYD88
Includes analysis of FLT3, NPM1, KIT, BRAF, MYD88