Newcastle Laboratories

Hepatitis B Core Antibody

Clinical Background:

This is a serological assay used to detect IgG antibodies to hepatitis B virus (HBV) core antigen (anti-HBc). Tests for PAST hepatitis B virus infection. In the abscence of HBsAg, detection of anti...

This is a serological assay used to detect IgG antibodies to hepatitis B virus (HBV) core antigen (anti-HBc). Tests for PAST hepatitis B virus infection. In the abscence of HBsAg, detection of anti-HBc indicates past, cleared infection. Seen in association with detectable HBsAg, anti-HBc indicates ongoing infection. Please note this assay can be affected by passively acquired antibody where blood products have been administered, or by maternally acquired antibodies in the first months of life.

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Test Details

  • Discipline:

    Microbiology

    Microbiology

  • Specimen Container Adult:

    Clotted blood - Gold SST

    Clotted blood - Gold SST

  • Specimen Container Paediatric:

    Clotted blood

    Clotted blood

  • Minimum Volume Adult:

    5 ml

    5 ml

  • Minimum Volume Paediatric:

    1 ml

    1 ml

  • Special Requirement:

    Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C

    Send to laboratory as quickly as possible. If delays likely, refrigerate at 2-8 deg C

  • Sample Stability:

    Stable for up to 24 hours

    Stable for up to 24 hours

  • Transport Requirements:

    Standard

    Standard

  • Add On Test:

    Possible up to 5 days

    Possible up to 5 days

  • Quality Assurance:

    UK National External Quality Assurance Scheme (UKNEQAS)

    UK National External Quality Assurance Scheme (UKNEQAS)

  • Reference Ranges:

    None available

    None available

  • Factors Affecting Result:

    If delays likely, refrigerate at 2-8 deg C

    If delays likely, refrigerate at 2-8 deg C

Availability:

Performed daily using random access systems. Can be processed outside core hours if sanctioned by the on-call virologist.

Turn Around:

2 days

Send To:

Department of Microbiology

Freeman Hospital
Freeman Road
Newcastle upon Tyne
NE7 7DN

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