Epidermal Antibodies
Clinical Background:
Epidermal antibodies are used in the diagnosis of blistering skin diseases. Antibodies to basement membrane of skin are positive in bullous pemphigoid (Pemphigoid Antibodies). Antibodies to interce...
Epidermal antibodies are used in the diagnosis of blistering skin diseases. Antibodies to basement membrane of skin are positive in bullous pemphigoid (Pemphigoid Antibodies). Antibodies to intercellular matrix of the epidermis are associated with pemphigus vulgaris (Pemphigus Antibodies).
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Special Requirement:
None
None
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Freq Analysis:
Fortnightly
Fortnightly
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
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Quality Assurance:
UK NEQAS for BULLOUS DERMATOSIS
UK NEQAS for BULLOUS DERMATOSIS
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Interpretation:
Additional information may be gained from direct immunofluorescence studies on skin biopsies (performed in the department of histopathology).
Additional information may be gained from direct immunofluorescence studies on skin biopsies (performed in the department of histopathology).
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Reference Ranges:
Pemphigoid Antibody Normal Range: Negative
Pemphigus Antibody Normal Range: Negative
Pemphigoid Antibody Normal Range: Negative
Pemphigus Antibody Normal Range: Negative
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Other Info:
Reported as Negative or a titration value for Positive samples.
Reported as Negative or a titration value for Positive samples.
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: