EMA
Clinical Background:
This test is most often performed as an aid to the diagnosis of Hereditary Spherocytosis (HS). This is an inherited abnormality of the red cell membrane, which results in spherical cells, which are...
This test is most often performed as an aid to the diagnosis of Hereditary Spherocytosis (HS). This is an inherited abnormality of the red cell membrane, which results in spherical cells, which are more fragile than normal. The resulting intravascular haemolysis leads to chronic haemolytic anaemia.
Test Details
-
Discipline:
Flow Cytometry
Flow Cytometry
-
Specimen Container Adult:
Purple top EDTA
Purple top EDTA
-
Specimen Container Paediatric:
Pink top paediatric EDTA
Pink top paediatric EDTA
-
Minimum Volume Adult:
0.5 mL
0.5 mL
-
Minimum Volume Paediatric:
0.5 mL
0.5 mL
-
Sample Stability:
24 hours
24 hours
-
Transport Requirements:
Ambient
Ambient
-
Freq Analysis:
As required
As required
-
Add On Test:
Use the contact details below to discuss if an add-on is required
Use the contact details below to discuss if an add-on is required
-
Reference Ranges:
Normal: 87 – 111% [previous ratio 0.89 – 1.13]
Hereditary Spherocytosis: 60 – 84% [previous ratio 1.16 – 1.69]
Pote...
Read MoreNormal: 87 – 111% [previous ratio 0.89 – 1.13]
Hereditary Spherocytosis: 60 – 84% [previous ratio 1.16 – 1.69]
Potentially indeterminate: 80 – 90% [previous ratio 1.1 – 1.2]
Results should always be interpreted in the context of counts, indices, film appearances and family history, but guide ranges are given above.
-
Factors Affecting Result:
Sample age and storage
Recent transfusion
Sample age and storage
Recent transfusion
-
Routine Contact Name:
Flow Cytometry Lab
-
Routine Telephone:
0191 282 5078
0191 282 5078
-
Routine Email: