D-Dimers
Clinical Background:
D-Dimer is one of the early products from the breakdown of cross-linked fibrin by the fibrinolytic system. It is used in the investigation of suspected DVT/PE and in the monitoring of DIC. The test...
D-Dimer is one of the early products from the breakdown of cross-linked fibrin by the fibrinolytic system. It is used in the investigation of suspected DVT/PE and in the monitoring of DIC. The test has a very high Negative Predictive Value (NPV) and is part of the Wells score used to determine likelyhood of thrombosis. The positive predictive value of the test is not as high and a positive result is not diagnotic of DVT/PE
Test Details
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Discipline:
Haemostasis
Haemostasis
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Specimen Container Adult:
Light blue - sodium citrate
Light blue - sodium citrate
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Specimen Container Paediatric:
Light blue - sodium citrate
Light blue - sodium citrate
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Minimum Volume Adult:
2.7mL
2.7mL
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Minimum Volume Paediatric:
1.3mL
1.3mL
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Special Requirement:
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
Tube must be correctly filled to line, to ensure correct ratio of blood to anticoagulant, ensure adequate mixing.
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Sample Stability:
8 hrs
8 hrs
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Transport Requirements:
Samples should be transported to lab without delay
Samples should be transported to lab without delay
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Freq Analysis:
Continuous
Continuous
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Add On Test:
tnu-tr.bloodsciencesadditions@nhs.net (external)
tnu-tr.bloodsciencesadditions@nhs.net (external)
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Quality Assurance:
UK NEQAS Blood Coagulation
UK NEQAS Blood Coagulation
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Reference Ranges:
Less than 230ng/mL. If used in DVT pathway <500 ng/ml
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
Read MoreLess than 230ng/mL. If used in DVT pathway <500 ng/ml
Note: For Haemostatic tests, paediatric reference ranges may be different to adult ranges. Please see
https://www.newcastlelaboratories.com/lab_service/core-247/
for details.
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Other Info:
A quantitative assay of fibrin degradation product D-Dimer.
A quantitative assay of fibrin degradation product D-Dimer.
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Routine Contact Name:
RVI or Freeman Section Leaders
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Routine Telephone:
RVI: 0191 2820332, Freeman: 0191 2231195
RVI: 0191 2820332, Freeman: 0191 2231195
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Specialist Test:
No
No
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Specialist Contact Name:
Haematology and Haemostasis Healthcare Scientist
Haematology and Haemostasis Healthcare Scientist
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Specialist Telephone:
0191 2139758
0191 2139758
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Specialist Email:
alison.brown93@nhs.net
alison.brown93@nhs.net