Newcastle Laboratories

Aquaporin 4 antibodies

Clinical Background:

Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally ex...

Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum

    Plasma is acceptable but CSF not required

    Serum

    Plasma is acceptable but CSF not required

  • Specimen Container Paediatric:

    Serum

    Plasma is acceptable but CSF not required

    Serum

    Plasma is acceptable but CSF not required

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    1 ml

    1 ml

  • Transport Requirements:

    Post at ambient temperature

    Post at ambient temperature

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@n...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

Sample sent to an external laboratory for analysis

Turn Around:

21 calendar days

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