Aquaporin 4 antibodies
Clinical Background:
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally ex...
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum or CSF
Serum or CSF
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Specimen Container Paediatric:
Serum or CSF
Serum or CSF
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
1 ml
1 ml
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to
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Quality Assurance:
IfQ autoantibodies against Neuronal antigens
IfQ autoantibodies against Neuronal antigens
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Reference Ranges:
Normal range:Negative
Normal range:Negative
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: