Newcastle Laboratories

Anti-Nuclear Antibodies

Clinical Background:

ANAs will be reported as part of an Autoantibody Screen. They are reported, either as Negative or as a titre (dilution) at which the ANA is last seen as positive. The pattern of ANA is also reporte...

ANAs will be reported as part of an Autoantibody Screen. They are reported, either as Negative or as a titre (dilution) at which the ANA is last seen as positive. The pattern of ANA is also reported as part of the Autoantibody Screen and this can give an indication of possible significant antibodies.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Daily

    Daily

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@n...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS for Antibodies to Nuclear and Related Antigens

    UK NEQAS for Antibodies to Nuclear and Related Antigens

  • Interpretation:

    Antinuclear antibodies may be associated with connective tissue diseases but are non-specific and may also occur in other conditions especially infections.

    Antinuclear antibodies may be associated with connective tissue diseases but are non-specific and may also occur in other conditions especially infections.

  • Reference Ranges:

    Adult Normal Range: <1/80

    Paediatric Normal Range: <1/20

    Adult Normal Range: <1/80

    Paediatric Normal Range: <1/20

  • Other Info:

    Reported as Negative or a titration value for Positive samples. ANA is useful in the diagnosis of SLE and other connective tissue diseases but is not a useful tool for assessing disease activity an...

    Reported as Negative or a titration value for Positive samples. ANA is useful in the diagnosis of SLE and other connective tissue diseases but is not a useful tool for assessing disease activity and response to treatment; serial measurement of ANA is therefore discouraged.

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  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

Autoantibody Screens are done daily, Monday to Friday, usually in the morning.

Turn Around:

2.5 routine working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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