Newcastle Laboratories

Anti-Neuronal Nuclear Antibody

Clinical Background:

Anti-Neuronal Nuclear Antibodies are also known as Hu antibodies and are specific for neuronal cell nuclei. They may be found in patients with paraneoplastic sensory neuropathy or encephalomyelitis...

Anti-Neuronal Nuclear Antibodies are also known as Hu antibodies and are specific for neuronal cell nuclei. They may be found in patients with paraneoplastic sensory neuropathy or encephalomyelitis associated with small cell carcinoma of the lung.

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Test Details

  • Discipline:

    Immunology

    Immunology

  • Specimen Container Adult:

    Serum-SST

    Serum-SST

  • Specimen Container Paediatric:

    Serum-Plain tube

    Serum-Plain tube

  • Minimum Volume Adult:

    1 ml

    1 ml

  • Minimum Volume Paediatric:

    0.5 ml

    0.5 ml

  • Special Requirement:

    None

    None

  • Freq Analysis:

    Fortnightly

    Fortnightly

  • Add On Test:

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@n...

    All urgent add ons via telephone on 0191 282 4766, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    or

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS for Paraneoplastic Antibodies

    UK NEQAS for Paraneoplastic Antibodies

  • Interpretation:

    None

    None

  • Reference Ranges:

    Normal Range: Negative

    Normal Range: Negative

  • Other Info:

    Reported as Negative, Weakly positive, Positive, or Strongly positive.

    Reported as Negative, Weakly positive, Positive, or Strongly positive.

  • Routine Contact Name:

    Autoimmunity Lab

  • Routine Telephone:

    0191 282 1890

    0191 282 1890

  • Routine Email:

Availability:

ANNA-1 are tested on a fortnightly basis as part of the same assay that tests for Purkinje Cell Antibodies (PCA).

Turn Around:

15 working days

Send To:

Department of Blood Sciences

Level 3
Leazes Wing
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP

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