Anti-CRMP5 Antibodies
Clinical Background:
Antibodies recognize the collapsin response-mediator brain protein (CRMP) family; CRMP5 is the dominant antigen. Associated with small cell lung cancer (SCLC) in 77% and thymoma in 6%.The syndrome ...
Antibodies recognize the collapsin response-mediator brain protein (CRMP) family; CRMP5 is the dominant antigen. Associated with small cell lung cancer (SCLC) in 77% and thymoma in 6%.The syndrome can include: subacaute sensory neuropathy; limbic encephalopathy; cereballar ataxia; extra-pyramidal syndromes; myopathy. The presence of antibodies to CV2/CRMP5 in SCLC is associated with better prognosis than anti-Hu antibodies.
Test Details
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Discipline:
Immunology
Immunology
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Specimen Container Adult:
Serum-SST
Serum-SST
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Specimen Container Paediatric:
Serum-Plain tube
Serum-Plain tube
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Minimum Volume Adult:
1 ml
1 ml
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Minimum Volume Paediatric:
0.5 ml
0.5 ml
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Special Requirement:
None
None
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Add On Test:
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address nuth.autoimmunity@nhs.net
All urgent add ons via telephone on 0191 2821890, and must be confirmed via email to the appropriate email address nuth.autoimmunity@nhs.net
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Interpretation:
None
None
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Reference Ranges:
Normal Range: Negative
Normal Range: Negative
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Other Info:
Reported as Negative or Positive
Reported as Negative or Positive
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Routine Contact Name:
Autoimmunity Lab
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Routine Telephone:
0191 282 1890
0191 282 1890
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Routine Email: