Newcastle Laboratories

Anti-cardiolipin (IgG)

Clinical Background:

Anticardiolipin antibodies are found in several disease states and may be an incidental finding with no clinical signficance or an indicator of a potentially severe underlying condition termed Anti...

Anticardiolipin antibodies are found in several disease states and may be an incidental finding with no clinical signficance or an indicator of a potentially severe underlying condition termed Anti-phospholipid Syndrome. The antibodies may be assoicated with increased thrombotic risk and recurrent miscarriage. This assay is part of the Thrombophilia Screen

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Yellow/Red - serum (no anticoagulant)

    Yellow/Red - serum (no anticoagulant)

  • Specimen Container Paediatric:

    Yellow/Red - serum (no anticoagulant)

    Yellow/Red - serum (no anticoagulant)

  • Minimum Volume Adult:

    2.7mL

    2.7mL

  • Minimum Volume Paediatric:

    1.3mL

    1.3mL

  • Special Requirement:

    Ensure adequate mixing.

    Ensure adequate mixing.

  • Sample Stability:

    24 hrs

    24 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    Weekly

    Weekly

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nh...

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    tnu-tr.bloodsciencesadditions@nhs.net (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Antiphospholipids

    UK NEQAS Antiphospholipids

  • Reference Ranges:

    <20 GPL-U/mL - Negative

    20 – 40 GPL-U/mL - Low Positive

    40 – 80 GPL-U/mL - Medium Positive

    >80 GPL-U/mL - High Positive

    <20 GPL-U/mL - Negative

    20 – 40 GPL-U/mL - Low Positive

    40 – 80 GPL-U/mL - Medium Positive

    >80 GPL-U/mL - High Positive

  • Other Info:

    Antibody directed against cardiolipin, a component of the inner mitochondrial membrane.

    Antibody directed against cardiolipin, a component of the inner mitochondrial membrane.

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 223 1780

    0191 223 1780

  • Routine Email:

    p.strong@nhs.net

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All testing performed at Freeman Haematology laboratory and available during routine hours, Monday - Friday. Testing is usually performed on a weekly basis, depending on batch size availability. This is an ELISA assay and may not be performed on same day as request depending on time recieved

Turn Around:

2 weeks

Send To:

Department of Blood Sciences

Freeman Hospital
Freeman Road
Newcastle upon Tyne
NE7 7DN

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