Newcastle Laboratories

Anti-B2 Glycoprotein 1 IgM

Clinical Background:

Anti-B2Glycoprotein 1 antibodies are a subset of antibodies tested for in the investigation of Antiphospholipid syndrome (APS). Patients who are positive for Anticardiolipin are then usually screen...

Anti-B2Glycoprotein 1 antibodies are a subset of antibodies tested for in the investigation of Antiphospholipid syndrome (APS). Patients who are positive for Anticardiolipin are then usually screened for anti-B2GP1 if APS is suspected. There is a strong correlation of Thrombotic risk in patients who are Lupus Anticoagulant (LA) positive and anti-B2GP1 positive

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Test Details

  • Discipline:

    Haemostasis

    Haemostasis

  • Specimen Container Adult:

    Yellow/Red - serum (no anticoagulant)

    Yellow/Red - serum (no anticoagulant)

  • Specimen Container Paediatric:

    Yellow/Red - serum (no anticoagulant) or Citrate (blue cap)

    Yellow/Red - serum (no anticoagulant) or Citrate (blue cap)

  • Minimum Volume Adult:

    2.7ml

    2.7ml

  • Minimum Volume Paediatric:

    1.3ml

    1.3ml

  • Special Requirement:

    If using a citrate sample tube it must be filled correctly to the line, ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

    If using a citrate sample tube it must be filled correctly to the line, ensure correct ratio of blood to anticoagulant, ensure adequate mixing.

  • Sample Stability:

    24 hrs

    24 hrs

  • Transport Requirements:

    Samples should be transported to lab without delay

    Samples should be transported to lab without delay

  • Freq Analysis:

    Weekly

    Weekly

  • Add On Test:

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs....

    All urgent add ons via telephone on 0191 28 24718, and must be confirmed via email to the appropriate email address

    RVIadditions.Laboratory@nuth.nhs.uk (internal)

    tnu-tr.bloodsciencesadditions@nhs.net (external)

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  • Quality Assurance:

    UK NEQAS Antiphospholipids

    UK NEQAS Antiphospholipids

  • Reference Ranges:

    0 - 6 GPLU/ml

    0 - 6 GPLU/ml

  • Routine Contact Name:

    Peter Strong

  • Routine Telephone:

    0191 282 0332

    0191 282 0332

  • Routine Email:

    peter.strong@nuth.nhs.uk

  • Specialist Test:

    Yes

    Yes

  • Specialist Contact Name:

    Haematology/Haemostasis Health care Scientist

    Haematology/Haemostasis Health care Scientist

  • Specialist Telephone:

    0191 213 9758

    0191 213 9758

Availability:

All testing performed at Freeman Haematology laboratory and available during routine hours, Monday - Friday. Testing is usually performed on a weekly basis, depending on batch size availability. This is an ELISA assay and may not be performed on same day as request depending on time recieved

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