Newcastle Laboratories

Alanine aminotransferase, serum

Clinical Background:

ALT is an intracellular cytoplasmic enzyme. It is widely distributed throughout the body’s tissues, with the greatest amounts in liver and the kidneys. It is a key enzyme in gluconeogenesis. ALT pr...

ALT is an intracellular cytoplasmic enzyme. It is widely distributed throughout the body’s tissues, with the greatest amounts in liver and the kidneys. It is a key enzyme in gluconeogenesis. ALT present in the plasma is presumed to be derived from the normal turnover of tissue cells; increased quantities are found in tissue damage (particularly hepatic cell damage).

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Specimen Container Adult:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Specimen Container Paediatric:

    Serum (SST or plain tube)

    Serum (SST or plain tube)

  • Minimum Volume Adult:

    1 mL blood

    1 mL blood

  • Minimum Volume Paediatric:

    0.5 mL blood

    0.5 mL blood

  • Sample Stability:

    Unseparated sample: 4 days
    Separate sample: 3 days at 15-25C, 7 days at 2-8C, >7 days at -80C

    Unseparated sample: 4 days
    Separate sample: 3 days at 15-25C, 7 days at 2-8C, >7 days at -80C

  • Reference Ranges:

    All ages: 0 - 40 U/L

    All ages: 0 - 40 U/L

  • Factors Affecting Result:





  • Other Info:

    Lithium heparin plasma sample also acceptable

    Lithium heparin plasma sample also acceptable

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

Availability:

24/7, analysed at RVI and Freeman

Turn Around:

Urgent: within 1 hour

Non-urgent: within 4 hours

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