Newcastle Laboratories

AFP, CSF

Clinical Background:

AFP is not normally expressed in the central nervous system (CNS). The presence of germinomas in the CNS and CNS involvement in metastatic cancer and meningeal carcinomatosis results in increased l...

AFP is not normally expressed in the central nervous system (CNS). The presence of germinomas in the CNS and CNS involvement in metastatic cancer and meningeal carcinomatosis results in increased levels of AFP in cerebrospinal fluid.

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Test Details

  • Discipline:

    Biochemistry

    Biochemistry

  • Minimum Volume Adult:

    0.5 mL CSF

    0.5 mL CSF

  • Minimum Volume Paediatric:

    0.5 mL CSF

    0.5 mL CSF

  • Special Requirement:

    CSF in plain tube

    CSF in plain tube

  • Interpretation:

    CSF AFP is valuble:-
    As an adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis
    Evaluating germ-cell tumors, including testicular cancer metastatic to th...

    CSF AFP is valuble:-
    As an adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis
    Evaluating germ-cell tumors, including testicular cancer metastatic to the CNS in conjunction with beta-human chorionic gonadotropin measurement
    As an adjunct in distinguishing between suprasellar dysgerminomas and craniopharyngiomas
    As a supplement to cerebrospinal fluid cytologic analysis

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  • Reference Ranges:

    Please note the method has not been validated for the measurement of AFP in CSF

    Please note the method has not been validated for the measurement of AFP in CSF

  • Routine Contact Name:

    Duty Biochemist

  • Routine Telephone:

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

    Freeman: 0191 244 8889
    RVI: 0191 282 9719

  • Routine Email:

    - For external users: TNU-Tr.duty.biochemist@nhs.net

    - For Trust users: DutyBiochemist@nuth.nhs.uk

Availability:

Available 24/7

Turn Around:

Within 2 full access days

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